Oesophageal cancer

In oesophageal cancer patients (n=158) treated with radiotherapy and PSK (3 g/day) for >3 months, raised serum a- 1anti-chymotrypsin levels were associated with a higher survival rate at 5 years than in the control group (55% versus 26%, p < 0.008)61.

Similarly, overall 5-year survival rate was also higher in patients with elevated serum sialic acid levels (58% vs 31%, p < 0.07) 59.   These findings are consistent with those reported for gastric cancer where patients with raised serum levels of tumour markers may benefit most from immunotherapy using PSK60.